Bone Height and Extractions Study

Alveolar Bone Loss Clinical Trial

Official title:

A Randomised Controlled Trial to Assess the Alveolar Bone Height Distal to Lower Second Molar Following Either Coronectomy or Extraction of the Adjacent Impacted Lower Third Molar

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03909568
• Other study ID #: 249253
• Status: Not yet recruiting
• Phase: N/A
• Start date: November 2019
• Est. completion date: August 2021

Study information

• Verified date: April 2019
• Source: King's College London
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

A coronectomy is often chosen over complete extraction of a lower third molar when the tooth appears to be in close proximity to the inferior dental (ID) canal, as assessed on a plain radiograph or a cone beam computer tomograph (CBCT). Following a coronectomy, the roots of the third molar may migrate in a coronal direction. This effect, along with the bone-preserving technique of a coronectomy over extraction, may provide increased bone height distal to the lower second molars, when compared to extraction. Partially erupted lower third molars, specifically those with mesio-angular impactions, are commonly associated with reduced bone height distal to lower second molars, and cause damage to the periodontal support of these neighboring teeth. It is assumed that maintenance of the impacted third molars or extraction of these teeth may compromise the periodontal status of the lower second molars. This study will investigate if coronectomy improves the bone levels, and therefore the periodontal status, of lower second molars, and may propose an indication for a coronectomy regardless of the proximity of the tooth to the ID canal.

Coronectomies were first proposed as a treatment option just over thirty years ago, but there are very few long-term studies on the procedure reported in the literature. To the best of the investigator's knowledge, this will be the first randomised controlled trial comparing the bone height distal to the lower second molar following a coronectomy or extraction of the lower third molar.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 50
• Est. completion date: August 2021
• Est. primary completion date: August 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patients requiring extraction of both lower third molars

• Both lower third molars to have mesio-angular impa

• ctions, as assessed by location of the contact point between the crown of the third molar and the cemento-enamel junction (CEJ) of the second molar and the angulation of the third molar

• Both lower third molars must lie above or clear of the ID canal as assessed on a plain radiograph or CBCT

• Presence of lower second molars

• Patients must be =18yrs old

• Patients willing to attend follow up appointments

Exclusion Criteria:

• Lower third molars with caries, periapical pathology or associated lesions such as cysts

• Patients who are immunocompromised, have a history of or due to have head and neck radiotherapy, chemotherapy, have previously been given or due to start intravenous bisphosphonates

• Smokers (>5 cigarettes/day)

• Patients involved in current research or have recently been involved with research prior to recruitment

Related Conditions & MeSH terms

• Alveolar Bone Loss
• Periodontal Attachment Loss
• Periodontal Pocket

Intervention

Procedure:
• Third molar surgery
Comparing complete removal of third molar with removal of crown only on contralateral side

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
King's College London

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Linear bone height distal to lower second molar tooth	Assessed by comparison of periapical radiographs pre- and post-intervention	Six months surgical intervention