Autogenous Bone Mixed With Xenograft Versus Xenograft Alone Versus Absorbent Gelatin Sponge

Alveolar Bone Loss Clinical Trial

Official title:

Alveolar Ridge Preservation in Mandibular Molars Using Mixture of Autogenous Bone & Anorganic Bovine Bone (ABB) Versus Anorganic Bovine Bone Alone Versus Absorbent Gelatin Sponge

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03584984
• Other study ID #: 2807
• Status: Not yet recruiting
• Phase: N/A
• Start date: August 1, 2018
• Est. completion date: July 1, 2019

Study information

• Verified date: July 2018
• Source: Cairo University
• Contact: Dina M. Al-Esawy, Masters
• Phone: 01206036365
• Email: dr.dina.alesawy[@]hotmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Alveolar bone atrophy post-extraction has been well documented in the past years. normal healing event results in a minimal loss of vertical height (around 1 mm), but a substantial loss of width in the buccal-lingual plane (4-6 mm). Alveolar socket preservation is thought to deal with this issue as to prevent the loss of alveolar bone dimensions post extraction in the case of delayed implant placement

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 30
• Est. completion date: July 1, 2019
• Est. primary completion date: January 1, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 50 Years

Eligibility

Inclusion Criteria:

• Adult patients with hopeless mandibular molars indicated for extraction and implant placement in two stages that indicate socket preservation.

• Both sexes.

• No intraoral soft and hard tissue pathology.

• No systemic condition that contraindicate implant placement.

Exclusion Criteria:

• Presence of fenestrations or dehiscence of the residual bony Walls after extraction.

• Heavy smokers more than 20 cigarettes per day .(24)

• Patients with systemic disease that may affect normal healing.

• Psychiatric problems

• Disorders to implant are related to a history of radiation therapy to the head and neck neoplasia, or bone augmentation to implant site.

• Patients that refuse to be called back for implant placement post extraction.

• Patients that have exceeded bone resorption surrounding the tooth prior to extraction and require guided bone regeneration.

• Pregnant Females.

Related Conditions & MeSH terms

• Alveolar Bone Loss
• Alveolar Bone Resorption
• Bone Graft Failure
• Bone Resorption

Intervention

Procedure:
• Mixture of Autogenous bone & Anorganic Bovine Bone (ABB)
Filling the socket with Mixing of autogenous bone graft and anorganic bovine bone in a 50:50 ratio
• Anorganic Bovine Bone (ABB)
Filling the socket with Anorganic bovine bone graft material only
• Absorbable gelatin sponge
Filling the socket with an absorbable gelatin sponge foam pack

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Histomorphometrical bone analysis	histological bone core analysis	6 month post primary surgery
Secondary	Alveolar Bone marginal loss	CBCT measurements of marginal bone dimensional difference	6 month post primary surgery