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A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD — RestorAATion-2  

Alpha-1 Antitrypsin Deficiency Clinical Trial

Official title:
A Phase 1b/2a Open-label Single Ascending Doses (SAD) and Multiple Ascending Doses (MAD) Research Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Participants With AATD Pi*ZZ on WVE-006 (RestorAATion-2)

Clinical Trial Summary

The purpose of this open-label study is to assess the safety, tolerability, pharmacodynamics, and pharmacokinetics of WVE-006 in participants with alpha-1 antitrypsin deficiency (AATD) following Period 1 single ascending dose (SAD) and Period 2 multiple ascending doses (MAD), respectively.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06405633
Study type Interventional
Source Wave Life Sciences Ltd.
Contact Clinical Operations
Phone 855-215-4687
Email Clinicaltrials@wavelifesci.com
Status Recruiting
Phase Phase 1/Phase 2
Start date June 2024
Completion date July 2025
View Details
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