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Recruiting
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NCT05687474 -
Baby Detect : Genomic Newborn Screening
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|
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Recruiting
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NCT03285100 -
The Effects of Discontinuation of Vitamin K Antagonists on the Rate of Elastin Degradation
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N/A |
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Completed
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NCT03636347 -
A 12-week Study Treating Participants Who Have alpha1-antitrypsin-related COPD With Alvelestat (MPH966) or Placebo.
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Phase 2 |
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Completed
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NCT00396006 -
Efficacy and Safety Study of Augmentation Therapy With ARALAST Fraction IV-1 (Human Alpha 1 - Proteinase Inhibitor)
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Phase 4 |
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Completed
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NCT04174118 -
Study of DCR-A1AT in Healthy Adult Volunteers
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Phase 1 |
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Completed
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NCT05579431 -
A Phase 1, First-in-human Study of VX-634
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Phase 1 |
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Recruiting
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NCT05856331 -
Study of INBRX-101 Compared to Plasma-derived A1PI Therapy in Adults With AATD Emphysema
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Phase 2 |
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Suspended
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NCT00571272 -
Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis (LOGIC)
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|
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Completed
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NCT02168686 -
Safety Dose Finding Study of ADVM-043 Gene Therapy to Treat Alpha-1 Antitrypsin (A1AT) Deficiency
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Phase 1/Phase 2 |
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Recruiting
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NCT04204252 -
Evaluate Efficacy and Safety of "Kamada-AAT for Inhalation" in Patients With AATD
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Phase 3 |
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Completed
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NCT00067756 -
4-PBA: Will it Increase the Level of Alpha 1-Antitrypsin(AAT) in Persons With AAT Deficiency?
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Phase 2 |
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Not yet recruiting
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NCT06389877 -
A Study to Evaluate the Safety and Efficacy of BEAM-302 in Adult Patients With Alpha-1 Antitrypsin Deficiency (AATD)
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Phase 1/Phase 2 |
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Completed
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NCT00295061 -
Comparison of Pharmacokinetic, Safety, Tolerability of Alpha-1 MP and Prolastin In Alpha1-antitrypsin Deficient Adults
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Phase 3 |
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Completed
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NCT00001462 -
Characterization of the Pathobiology of Early Lung Destruction in Alpha 1-Antitrypsin Deficient Individuals
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N/A |
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Active, not recruiting
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NCT05297812 -
Alpha-1 Antitrypsin Disease Cohort: Longitudinal Biomarker Study of Disease
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|
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Completed
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NCT03114020 -
Efficacy/Safety of HA Inhalation Solution for Hereditary Emphysema in Patients With Alpha-1 Antitrypsin Deficiency
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Phase 2 |
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Completed
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NCT00460096 -
Phase II/III Study of an Alpha-1 Proteinase Inhibitor (Kamada-API) in Individuals With Alpha-1 Antitrypsin Deficiency
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Phase 2/Phase 3 |
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Completed
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NCT00377416 -
Experimental Gene Transfer Procedure to Treat Alpha 1-Antitrypsin Deficiency
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Early Phase 1 |
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Terminated
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NCT00005098 -
Study of Genotype and Phenotype in Patients With Alpha 1-Antitrypsin Deficiency
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N/A |
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Completed
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NCT03362242 -
Study of ARO-AAT in Normal Adult Volunteers
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Phase 1 |