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Alopecia Areata clinical trials

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NCT ID: NCT01189279 Completed - Alopecia Clinical Trials

Safety and Pharmacokinetics Study of New Formulation of Bimatoprost in Patients With Alopecia

Start date: October 2010
Phase: Phase 1
Study type: Interventional

This study will investigate the safety, tolerability, and pharmacokinetics of new formulation of bimatoprost following topical application in patients with alopecia. Two formulations of bimatoprost will be investigated in Part 1 and a third formulation of bimatoprost will be investigated in Part 2. Part 2 will begin after Part 1 has completed.

NCT ID: NCT01167946 Completed - Alopecia Totalis Clinical Trials

Safety and Efficacy of Oral Mega Pulse Methylprednisolone in Severe Therapy Resistant Alopecia Areata

Start date: January 2003
Phase: Phase 4
Study type: Interventional

Systemic Pulse Glucocorticoids have been shown to be effective in widespread Alopecia areata but not the totalis, universalis or ophiasic type. Whether the failure is due to inadequate dosing, inadequate frequency or other factors is a matter of debate. The investigators decided to conduct this study using the oral pulse steroid, however with higher doses and more frequent pulses to patients with severe forms of Alopecia areata.

NCT ID: NCT01145625 Completed - Alopecia Clinical Trials

Clinical Trial in Females With Female Pattern Hair Loss

Start date: June 2010
Phase: Phase 3
Study type: Interventional

This is a year-long clinical trial to evaluate the effectiveness and safety in women with Female Pattern Hair Loss (FPHL), comparing a new 5% minoxidil topical foam (MTF) formulation applied once a day versus the 2% minoxidil topical solution (MTS) applied twice a day. This clinical trial uses an objective measurement called Target Area Hair Count (TAHC) to evaluate if there is a change in the number of hairs in the area being examined after using the product for 24 weeks (and also after using the product for 12 Weeks and for 52 weeks). This trial will determine if the benefit of using either study product outweighs the risks.

NCT ID: NCT01052870 Completed - Clinical trials for Androgenetic Alopecia

Association of Polymorphisms in the Androgen Receptor Gene and Finasteride Response in Women With Androgenetic Alopecia

Start date: December 2008
Phase: Phase 1
Study type: Interventional

Previous studies of finasteride treatment in women with hair loss have failed to show positive results, yet, some women have responded anecdotally. Given that polymorphisms of the androgen receptor gene which confer androgen sensitivity impact male response to finasteride therapy, it was hypothesized that the same polymorphism in women may identify the group that will respond. This study is designed to test the impact of finasteride therapy on hair loss in postmenopausal women.

NCT ID: NCT01023841 Completed - Alopecia Areata Clinical Trials

Safety and Efficacy of Bimatoprost Solution in Treating Eyelash Loss or Hypotrichosis in Children

Start date: June 1, 2010
Phase: Phase 4
Study type: Interventional

This study will evaluate the safety and efficacy of bimatoprost solution 0.03% once daily application to the upper eyelid margins compared with vehicle in treating eyelash loss or hypotrichosis (inadequate or not enough eyelashes) in children.

NCT ID: NCT01016964 Completed - Clinical trials for Androgenetic Alopecia

Treatment of Androgenetic Alopecia in Females, 12 Beam

Start date: January 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the efficacy of the HairMax LaserComb 2009 12 beam model for androgenetic alopecia in females when treatment is applied as directed.

NCT ID: NCT01008774 Completed - Neoplasms Clinical Trials

START: Swiss Taxotere Alopecia Prevention Trial

Start date: July 2009
Phase: N/A
Study type: Interventional

Primary objective: - Rate of complete chemotherapy induced alopecia (WHO grade III or IV, physician grading) Secondary objective: - Compliance to scalp cooling procedure - Received number of cycles of chemotherapy in each subgroup - Patient perception of scalp cooling procedure - Side effects of scalp cooling systems

NCT ID: NCT01004809 Completed - Alopecia Clinical Trials

AVODART® Alopecia Post-marketing Surveillance (PMS)

AVODART®PMS
Start date: April 29, 2010
Phase:
Study type: Observational

Post-marketing surveillance(PMS) to monitor the safety and effectiveness of dutasteride in Korean androgenetic alopecia patients

NCT ID: NCT00997815 Completed - Clinical trials for Recalcitrant Alopecia Universalis

The Randomized Double-blind Placebo-controlled Trial of Intralesional Botulinum Toxin A Injection for Recalcitrant Alopecia Totalis and Alopecia Universalis

Start date: December 2009
Phase: Phase 2/Phase 3
Study type: Interventional

The main purpose of this study is to determine the efficacy of intralesional botulinum toxin type A injection for recalcitrant alopecia totalis and alopecia universalis. Treatments of recalcitrant alopecia totalis and universalis remains an challenge issue for medical practice.The application of diphenylcyclopropenone (DPCP) is still being an standard treatment for the condition, however, there are at least thirty percentage of patients recalcitrant to this treatment. The complete etiology of this disease has yet to be clear.Nevertheless,recent studies have demonstrated the hypothesis of neurotransmitter involvements. There is numerous evidence in support of an imbalance of transmitters, including substance P and Calcitonin gene-related peptide. Botulinum toxin A injection has been used to treat a neuralgiform headache and diffused alopecia areata. Both headache and hair loss have been made much in improvement. This data may support the neurotransmitter imbalance theory. The investigators have been informed about possible effects to the alopecia condition, therefore, this study is conducted to assess the efficacy of botulinum toxin A as the novel treatment for recalcitrant alopecia totalis and alopecia universalis.

NCT ID: NCT00981461 Completed - Clinical trials for Androgenetic Alopecia

Treatment of Androgenetic Alopecia in Females, 9 Beam

Start date: October 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the efficacy of the HairMax LaserComb 2009 9 beam model in promoting hair growth in females diagnosed with androgenetic alopecia when treatment is applied as directed.