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Alopecia Areata clinical trials

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NCT ID: NCT01929330 Completed - Alopecia Clinical Trials

Bioequivalence Study of Dutasteride Five 0.1 mg and One 0.5 mg Soft Gelatin Capsules in Healthy Male Volunteers

Start date: September 23, 2013
Phase: Phase 1
Study type: Interventional

The aim of this study is to determine the bioequivalence of 5 x 0.1 milligram (mg) capsules compared to 1 x 0.5 mg capsule of dutasteride in healthy male subjects. The results of this study are expected to support registration applications for androgenetic alopecia (AGA) in Japan and other international markets.

NCT ID: NCT01904721 Completed - Alopecia Clinical Trials

A Safety and Efficacy Study of Bimatoprost in Men With Androgenic Alopecia (AGA)

Start date: August 2013
Phase: Phase 2
Study type: Interventional

This is a safety and efficacy study of bimatoprost in male subjects with androgenic alopecia (AGA).

NCT ID: NCT01900041 Completed - Clinical trials for Female Pattern Hair Loss

A Study to Evaluate the Superiority, Efficacy and Tolerability of Combination Pantovigar With 2% Minoxidil vs 2% Minoxidil in Women With Female Pattern Hair Loss

Start date: April 2012
Phase: Phase 2
Study type: Interventional

Pantovigar - a high effective product designed primarily for the treatment of diffuse hair loss in women as well as for the treatment of damaged hair, in the combined therapy can be successfully applied in other types of alopecia. The purpose of this study is to evaluate efficacy and tolerability of combination therapy Pantovigar plus 2% minoxidil vs 2% minoxidil. To collect tolerability data for combined treatment Pantovigar plus 2% Minoxidil course therapy.

NCT ID: NCT01852487 Completed - Androgenic Alopecia Clinical Trials

Effect of Pumpkin Seed Oil on Hair Growth in Men With Androgenetic Alopecia

Start date: February 2012
Phase: N/A
Study type: Interventional

Androgenic alopecia is the most common cause of hair loss in men. Finasteride and minoxidil are available in treatment of androgenetic alopecia, although the former causes decreased libido or ejaculate volume, erectile dysfunction, the latter causes scaling, itching of the scalp. Recently, Pulpkin Seed Oil shows some improved clinical efficacy on scalp hair growth in men with androgenetic alopecia, but there is no evidence to support this. The investigators conducted a randomized, double-blind, placebo-controlled efficacy and tolerability trial of Pumpkin seed oil (400mg/day)therapy in male patients with androgenetic alopecia.

NCT ID: NCT01831791 Completed - Alopecia Clinical Trials

A Long-term Study to Determine Safety and Efficacy of Dutasteride in Male Subjects With Androgenetic Alopecia

Start date: April 14, 2013
Phase: Phase 3
Study type: Interventional

This is a multicentre, open-label study to assess the safety, tolerability, and efficacy of 0.5 mg Dutasteride administered once daily for 52 weeks in men with Androgenetic Alopecia types III vertex, IV and V per the Norwood-Hamilton classification. The study consists of a Screening Phase (3 weeks prior to Baseline) and a Treatment Phase (52 weeks). A subject who completes the full course of study treatment and the final study visit (Week 52; Visit 7) will be considered as study completion.

NCT ID: NCT01797432 Completed - Alopecia Areata Clinical Trials

Combined Restylane and Triamcinolone Acetonide Injections for the Treatment of Alopecia Areata

Start date: March 2009
Phase: Phase 2
Study type: Interventional

The investigators hypothesize that Restylane® could serve as a repair matrix which also maintains IL triamcinolone acetonide concentrations at higher levels for a longer period of time in the skin, giving a more sustained local anti-inflammatory effect and thus, arresting the AA process and promoting hair regrowth. Furthermore, the combination of Restylane® with IL triamcinolone acetonide injections may prevent a common side effect, atrophy. With the prevention of scalp atrophy and the preservation of higher concentrations of triamcinolone acetonide for longer periods of time, patients may see a better clinical response for a longer period of time. Quality of life may improve as the number of clinic visits decreases as would the number of IL corticosteroid injections.

NCT ID: NCT01701271 Completed - Clinical trials for Androgenetic Alopecia

Efficacy Study of a Cosmetic Lotion in the Treatment of Androgenetic Alopecia in Males and Females

MEXISPATENT
Start date: February 2001
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether the Hair Loss Prevention Lotion named MEXIS, M.P.A.F., M6S PATENT is effective in the treatment of Androgenetic Alopecia.

NCT ID: NCT01669746 Completed - Clinical trials for Androgenetic Alopecia

A Study to Evaluate and Compare Injections of Autologous Mixed Population of Dermal Cells Cells Into the Balding Scalp of Subjects With Hair Loss (CA-0006931)

Start date: June 2012
Phase: Phase 2
Study type: Interventional

Evaluate the ability of injections of Ji Gami(TM) CN to induce hair growth in male and female subjects with hair loss.

NCT ID: NCT01559584 Completed - Alopecia Areata Clinical Trials

Phototoxic Doses of Ultraviolet A for Treatment of Alopecia Areata

Start date: March 2012
Phase: N/A
Study type: Interventional

Alopecia areata (AA) is a disease of the hair follicles with multifactorial etiology and a strong component of autoimmune origin. It is characterized by non-scarring hair loss on the scalp or any hair-bearing surface. Various therapeutic agents have been described for the treatment of AA, but none are curative or preventive. The aim of AA treatment is to suppress the activity of the disease. Phototherapy in the form of topical psoralen and ultraviolet A (PUVA) has been a well documented therapy for AA since 1978. A more recent technique of topical PUVA, namely phototoxic PUVA, has been adopted in two previous studies. Sessions were carried out once every 3 months, and a higher efficacy with more encouraging response rates in comparison to the conventional PUVA therapy has been documented. This assumed upper hand over the conventional PUVA might be due to increasing the amount of UV reaching the hair follicle cells and the surrounding inflammatory cells. Also it has been suggested that it might play a role as a powerful initiating agent of suppression through direct action at the DNA level. However, still the exact effect of this treatment has not been fully clarified.

NCT ID: NCT01520077 Completed - Alopecia Areata Clinical Trials

Vytorin in the Treatment of Alopecia Areata

Start date: July 2011
Phase: Phase 1
Study type: Interventional

Subjects, non pregnant/lactating and over 18years old, with 40% alopecia areata will take vytorin (statin/ezetimibe) for 24 or 52 weeks and be monitored for hair regrowth. The investigators hypothesize that Vytorin medication may have an effect on the inflammatory process of alopecia areata. Inactivating the inflammatory process may help in permitting hair regrowth in those subjects.