Allergy Clinical Trial
— Tro-BRAOfficial title:
Tromsø Birch Rust Allergy Study. Allergy to Birch Rust Fungi, a Possible Explanation to Seasonal Airway Allergy During Autumn? A Pilot Study With 30 Patients With Suspected Allergy to Birch Rust and 15 Non-allergic Controls.
In this project we study if spores from birch rust fungi (Melampsoridium Betulinum = MB) may be the eliciting allergen in patients with seasonal airway allergy during autumn in North Norway. Patients with suspected allergy to MB are compared with non-allergic controls using data about allergic disease and daily allergic symptoms during autumn. Daily spread of MB spores are compared with daily variations in allergic symptoms. Sensitization to MB and MB allergy are tested with skin prick test, specific immunoglobulin E (IgE) in serum, nasal provocation test and basophil activation test (BAT).
Status | Recruiting |
Enrollment | 45 |
Est. completion date | December 1, 2021 |
Est. primary completion date | December 1, 2021 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 75 Years |
Eligibility | Inclusion Criteria: - Self reported seasonal airway allergic symptoms during autumn Exclusion Criteria: - Perennial airway allergic symptoms without worsening during autumn |
Country | Name | City | State |
---|---|---|---|
Norway | University Hospital of North Norway | Tromsø |
Lead Sponsor | Collaborator |
---|---|
University Hospital of North Norway | Luxembourg Institute of Health, Oslo University Hospital |
Norway,
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* Note: There are 14 references in all — Click here to view all references
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Allergy to Birch rust fungi | Allergic symptoms during spread of Birch rust spores and positive sensitization and nasal provocation test to birch rust fungi. | 1st of August to 15th of October 2020 |
Status | Clinical Trial | Phase | |
---|---|---|---|
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