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Allergic Transfusion Reactions in Plasma Transfusion

Allergy Clinical Trial

Official title:
Risk Factors for Allergic Transfusion Reactions in Patients Receiving Plasma Transfusion

Clinical Trial Summary

Allergic transfusion reactions are a common complication of transfusion by blood components containing plasma. This study aims to investigate passive transfer of Immunoglobin E antibodies as a risk factor of allergic reactions to plasma transfusion by use of Solvent Detergent plasma.

Clinical Trial Description

Prospective observation study, aiming to measure transfer of Immunoglobin E antibodies and other factors associated with allergic complications in patients receiving plasma transfusion. Samples from patients and plasma units will be investigated. Samples frozen until investigation. To assess biological relevance of findings, additional analysis of basophil reactivity will be performed and information on clinical allergy collected by use of a questionaire . In-patients will be recruited if receiving plasma transfusion during surgery or if an allergic transfusion complication occurs. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02200692
Study type Observational
Source Haukeland University Hospital
Contact
Status Completed
Phase
Start date June 2014
Completion date March 2018
View Details
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