Allergy Clinical Trial
Food allergy is a potentially life threatening condition. The current practice consists of
elimination diet and injectable epinephrine in case of a reaction.
Recently, oral immunotherapy has emerged as a treatment for food allergy in milk eggs and
peanuts.
We conduct an oral immunotherapy program with ~500 patients so far. In this study we intent
to follow patients who completed the program and assess their allergy status and quality of
life.
Food allergy is a potentially life threatening condition. The current practice consists of
elimination diet and injectable epinephrine in case of a reaction.
Recently, oral immunotherapy (OIT) has emerged as an treatment for food allergy in milk eggs
and peanuts. Since 4/2010,a clinical OIT program for milk eggs and peanuts is performed at
the Institute fir Allergy Asthma and Immunology at Assaf Harofeh Medical Center with ~500
patients so far. Patients with IgE-mediated food allergy that are >4 years old are eligible.
In this study we intent to follow patients who completed the program. Patients will fill a
questionnaire regarding current consumption of the allergenic food, adverse reactions
experienced and treatments required including the use of EpiPen. Patients underwent skim
prick tests (SPT) for the allergenic food prior to initiation and treatment and will undergo
SPT again upon entering the study. Blood tests for IgE, IGG4, basophil activation and
cytokines will be obtained.
Patients who are not consuming the allergenic food regularly will undergo an oral food
challenge in clinic.
;
Observational Model: Cohort, Time Perspective: Cross-Sectional
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Terminated |
NCT02032056 -
Effect of Probiotics in Reducing Infections and Allergies in Young Children During the Complementary Feeding Period
|
N/A | |
| Completed |
NCT01842711 -
Cumulative Irritation Patch Test
|
N/A | |
| Completed |
NCT01633840 -
New Validated Recipes for Double-blind Placebo-controlled Low Dose Food Challenges
|
N/A | |
| Completed |
NCT00554983 -
Efficacy and Safety From a Recombinant Folding Variant of Bet v 1
|
Phase 3 | |
| Completed |
NCT00997971 -
Growth, Tolerance in Healthy Infants Fed a Partially Hydrolyzed Rice Protein
|
Phase 3 | |
| Completed |
NCT00331929 -
Respiratory Health Study of Children in Kiryat Tivon
|
N/A | |
| Completed |
NCT00232518 -
Randomised Controlled Clinical Trials of the Effect of Therapeutic Hookworm Infection in Allergic Rhinoconjunctivitis
|
N/A | |
| Completed |
NCT00220753 -
Air Cleaners for Children and Adolescents With Asthma and Dog Allergy
|
N/A | |
| Completed |
NCT04126096 -
Negative Predictive Value and NIC of Beta-Lactam Antibiotics.
|
N/A | |
| Completed |
NCT04046731 -
Neuromuscular Blocking Agents Utilized During Perioperative Hypersensitivity Evaluation
|
N/A | |
| Completed |
NCT04004351 -
Treatment Modalities in Children and Adolescents Suffering From HDM-induced Allergic Rhinitis and/or Asthma
|
||
| Not yet recruiting |
NCT05997784 -
Study of Indoor Air Pollutants and Their Impact in Childhood Health and Wellbeing
|
||
| Completed |
NCT04418999 -
Safety and Efficacy of Intracanalicular Dexamethasone Compared to Loteprednol Etabonate in Patients With Keratoconus
|
Early Phase 1 | |
| Completed |
NCT04186949 -
Early Origins of Allergy and Asthma
|
||
| Completed |
NCT02127801 -
Single Ascending-dose Study of the Efficacy, Safety, Tolerability, and Pharmacokinetics of REGN1908-1909 in Allergic, Adult Participants
|
Phase 1 | |
| Enrolling by invitation |
NCT05011071 -
The Alberta BLOOM Premature Child Study
|
||
| Not yet recruiting |
NCT06330974 -
Allergy, Asthma, and Atopic Eczema in Finland
|
||
| Completed |
NCT02596321 -
A Study Investigating the Immunologic Effects and Safety of 60-day Treatment of the ALK HDM Tablets in Adult Subjects With HDM-Induced Allergic Rhinitis and/or Atopic Asthma
|
Phase 3 | |
| Terminated |
NCT02601690 -
Observational Analysis of T Cell Responses to SPIREs for Multiple Allergens in Subjects With Allergy in North America
|
||
| Completed |
NCT02306473 -
The Leaky Lung Test
|
Early Phase 1 |