Nebulized Resveratrol Plus Carboxymethyl-β-Glucan for Reducing IL-5 in

Status Completed

Clinical Trial Summary

Single-center, randomized, placebo-controlled study to:

- characterize the subjects at baseline and discriminate groups of children based on IL-5, IL-17, IL-23 and INF-γ;

- investigate the effect of Resveratrol plus Carboxymethyl-β-Glucan, two sprays (100µL/spray) for nostril three times/day for 4 weeks, in comparison with placebo, in reducing nasal interleukin-5 (IL-5) in children with Allergic Rhinitis (AR).

Secondary objectives are to examine the effect of resveratrol plus carboxymethyl-β-glucan, in comparison with placebo, on subjective parameters, i.e. symptom scores, visual analogue scales for rhinitis, quality of life and quality of sleep, and the effect on objective parameters, i.e. nasal nitric oxide (nNO) levels, nasal cytology and acoustic rhinometry.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03349619
Study type	Interventional
Source	Istituto per la Ricerca e l'Innovazione Biomedica
Contact
Status	Completed
Phase	Phase 4
Start date	March 5, 2018
Completion date	July 31, 2018

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See also
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Nebulized Resveratrol Plus Carboxymethyl-β-Glucan for Reducing IL-5 in Children With Allergic Rhinitis — RENIM

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms