Allergic Rhinitis Clinical Trial
Official title:
A Double-blind, Randomized, Placebo-controlled, Cross-over, Allergen Challenge Study to Evaluate the Efficacy, Safety and Tolerability of BLX-028914 in Subjects With Allergic Rhinitis
This is a phase II study in patients with seasonal allergic rhinitis (SAR) and will compare
the effect versus placebo of two different oral doses of BLX-028914 in an allergen challenge
model. BLX-028914, a selective phosphodiesterase-4 (PDE4) inhibitor with a promising safety
profile,is currently under development for treatment of airway diseases by Orexo AB, Sweden.
The aim of this study is to compare the effect, safety and tolerability of 14 days treatment
with BLX-0289014 in patients with SAR in an allergen challenge model versus placebo.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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