Effects of Different Assisted Mechanical Ventilation in Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) Patients: Pressure Support Ventilation (PSV), Neurally Adjusted Ventilatory Assist (NAVA) and Controlled by Patient

ALI/ARDS Patients Clinical Trial

Official title:

Effects of Different Assisted Mechanical Ventilation in ALI/ARDS Patients: PSV, NAVA and Controlled by Patient

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00576771
• Other study ID #: 222222
• Status: Completed
• Phase: N/A
• First received: December 18, 2007
• Last updated: April 27, 2015
• Start date: August 2013
• Est. completion date: November 2014

Study information

• Verified date: April 2015
• Source: Policlinico Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: Italy: Ministry of Health
• Study type: Interventional

Clinical Trial Summary

The investigators' aim is to study the effect of pressure support ventilation versus neurally adjusted assist (NAVA) and controlled by patient in mechanically ventilated ALI/ARDS subjects.

Description:

In this study, PSV is compared with NAVA and assisted mechanically ventilation controlled by patient through a button. Inclusion criteria are: assisted mechanically ventilated ALI/ARDS patients.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 15
• Est. completion date: November 2014
• Est. primary completion date: November 2014
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• ALI/ARDS patients

Exclusion Criteria:

• Haemodynamic instability

• Barotrauma

• COPD

Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Acute Lung Injury
• ALI/ARDS Patients
• Respiratory Distress Syndrome, Adult
• Respiratory Distress Syndrome, Newborn

Intervention

Procedure:
• PSV
Pressure Support Ventilation
• NAVA
Neurally Adjusted Ventilatory Assist
• patient-controlled
assisted controlled MV through a button

Locations

Country	Name	City	State
Italy	Policlinico Hospital	Milan

Sponsors (1)

Lead Sponsor	Collaborator
Policlinico Hospital

Country where clinical trial is conducted

Italy, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Respiratory mechanics work of breathing,end expiratory lung volume, gas exchange, dead space, patient's comfort level		30 minutes	No