Medication Development in Alcoholism: Acamprosate Versus Naltrexone

Status Completed

Clinical Trial Summary

The purpose of this study is to develop and validate a human laboratory model for prediction of medication efficacy in clinical trials for relapse prevention in alcohol dependence. This study involves two laboratory sessions and an fMRI scan.

Clinical Trial Description

This is a double-blind, 3-cell, outpatient human laboratory study to determine the degree to which acamprosate and naltrexone will suppress subjective and physiological responsivity to alcohol cues relative to placebo in early abstinence. ;

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor)

Related Conditions & MeSH terms

Alcoholism

Clinical Trial Details

NCT number	NCT00656630
Study type	Interventional
Source	The Scripps Research Institute
Contact
Status	Completed
Phase	Phase 2
Start date	December 2007
Completion date	January 2010

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