Alcoholic Intoxication, Chronic Clinical Trial
Official title:
Does the Threat of an Aversive Reaction Affect Craving of Alcohol During Cue Exposure in Alcohol Dependent Patients?
Verified date | February 2007 |
Source | Assistance Publique - Hôpitaux de Paris |
Contact | n/a |
Is FDA regulated | No |
Health authority | France: Ministry of Health |
Study type | Interventional |
To evaluate the effect of the threat of an aversive reaction on the response during alcohol cue exposure in alcohol dependent patients : (1) the subjective response (craving) and (2) the physiological response (heart rate and blood pressure).
Status | Completed |
Enrollment | 30 |
Est. completion date | March 2009 |
Est. primary completion date | March 2009 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Inpatients - Alcohol dependence - Detoxified since at least one week - Willing to abstain from alcohol for at least 6 months - Never treated with disulfiram Exclusion Criteria: - Any contra-indication to disulfiram - Treated with and antidepressant or a neuroleptic medication within the 30 previous days - Treated with acamprosate, naltrexone, betablockers or clonidine within the 7 previous days - Treated with benzodiazepines within the 3 previous days (except diazepam, maximum 30 mg/d) - Anosmia |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
France | Hopital Emile Roux APHP | Limeil-Brevannes |
Lead Sponsor | Collaborator |
---|---|
Assistance Publique - Hôpitaux de Paris | Institut de Recherches Scientifiques sur les Boissons |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Alcohol craving visual analogic evaluation | Alcohol craving visual analogic evaluation | during de study | Yes |
Secondary | Blood Pressure and Pulse Rate | Blood Pressure and Pulse Rate | during the study | Yes |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
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