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Utility of the Use of N-acetylcysteine Associated With Conventional Treatment in Patients With Severe Acute Alcoholic Hepatitis (Maddrey> 32)

Alcoholic Hepatitis Clinical Trial

Official title:
Utility of the Use of N-acetylcysteine Associated With Conventional Treatment in Patients With Severe Acute Alcoholic Hepatitis (Maddrey> 32)

Clinical Trial Summary

This study is designed to evaluate the hypothesis that patients with severe acute alcoholic hepatitis have lower morbi-mortality if the patients receive treatment with corticosteroids + NAC, compared to patients that only receive corticosteroids.

Clinical Trial Description

Currently there are no drugs available to cure patients with acute alcoholic hepatitis. The only treatment available is corticosteroids, the efficacy of which is limited and not free of side effects. Other drugs that can contribute to improve the situation of patients with this entity is N-acetylcysteine (NAC), however, in the different studies contradictory data are obtained, therefore, different societies recommend conducting studies of greater scope to confirm the effectiveness of N-acetylcysteine and to be able to make a clear indication about N-acetylcysteines use. Clinical, randomized, controlled, multicenter, parallel and open trial. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05294744
Study type Interventional
Source Bioaraba Health Research Institute
Contact Ana Belén Fernández, Clinic
Phone 945007000
Email anabelen.fernandezlaso@osakidetza.eus
Status Not yet recruiting
Phase N/A
Start date April 2022
Completion date July 2023
View Details
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