Medication Development in Alcoholism: Suvorexant Versus Placebo

Status Completed

Clinical Trial Summary

The primary hypotheses under test are that alcohol dependent subjects treated with suvorexant will report decreased craving for alcohol following alcohol exposure in the laboratory and report significantly less drinking under naturalistic conditions, than those treated with placebo. Suvorexant (Belsomra®) received approval by the FDA in 2014 for treatment of insomnia. To control for any effect of pre-existing sleep disturbance for which suvorexant may be indicated, subjects will be stratified on the basis of a Pittsburgh Sleep Quality Index total score of > 5 versus <5. Subjects were also stratified by sex.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04229095
Study type	Interventional
Source	The Scripps Research Institute
Contact
Status	Completed
Phase	Phase 2
Start date	November 17, 2021
Completion date	November 8, 2022

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