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Alpha-1 Blockade for Alcohol Use Disorder (AUD) — DOXY  

Alcohol Use Disorder (AUD) Clinical Trial

Official title:
A Focus on Alpha-1 Blockade as a Novel Pharmacological Treatment for AUD

Clinical Trial Summary

The goal of this research is to replicate findings previously conducted in a pilot trial and to understand, mechanistically, the role of stress in the development of AUD pharmacotherapies that target noradrenergic blockade.

Clinical Trial Description

16 week, between-subject, double-blind, randomized clinical trial (RCT) with doxazosin (16 mg, or maximum tolerated dose, MTD) compared to placebo in 184 treatment seeking individuals with AUD ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04135846
Study type Interventional
Source Brown University
Contact Zoe L Brown, BA
Phone 401-863-6646
Email alcohol.stress.study@brown.edu
Status Recruiting
Phase Phase 2
Start date December 19, 2019
Completion date December 20, 2024
View Details
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