Mechanisms for Alcohol Treatment Change [MATCH] Study

Alcohol Consumption Clinical Trial

— MATCH  

Official title:

Mechanisms for Alcohol Treatment Change [MATCH] Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02918565
• Other study ID #: STUDY19050262
• Secondary ID: R01AA023650
• Status: Completed
• Phase: N/A
• Start date: December 2016
• Est. completion date: November 22, 2021

Study information

• Verified date: November 2023
• Source: University of Pittsburgh
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

A 5-arm randomized trial to determine what components of a text message intervention are necessary to reduce hazardous drinking among young adults and mechanisms through which these changes occur.

Description:

Young adults ages 18-25 have high rates of hazardous alcohol use and alcohol-related consequences. The Emergency Department (ED) provides an important opportunity to identify young adult hazardous drinkers who could benefit from interventions. A Text Message (TM) intervention was shown to reduce alcohol consumption among young adult ED patients, showing durable effects over 9-months. The TM intervention uses behavior change techniques with the largest effect sizes in an alcohol intervention meta-analysis: "goal commitment" and "self-monitoring", along with real-time "feedback". However, the unique effect of these ingredients, and mechanisms (processes occurring within the individual) through which they operate to reduce drinking remain unclear, a critical gap addressed by this project. Young adult ED patients (ages 18-25) who screen positive for hazardous drinking will be recruited to participate in a randomized trial to determine how best to help individuals reduce hazardous drinking. All participants will be asked to complete web-based surveys at baseline, 12 and 24 weeks after enrollment, complete brief psychomotor tasks weekly for 14 weeks, and respond to text messages each Thursday and Sunday for the next 12 weeks. Those randomized to the TM interventions will additionally receive feedback on their text reports. The four TM intervention arms are: (1) Drinking Cognition Feedback (DCF), (2) Alcohol Risk Feedback (ARF), (3) Adaptive Goal Support (AGS) and (4) a combination of DCF, ARF, and AGS=COMBO). Study results have implications for designing efficient mobile interventions, and developing a dynamic theory of behavior change.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 1131
• Est. completion date: November 22, 2021
• Est. primary completion date: November 22, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 25 Years

Eligibility

Inclusion Criteria:

• total score of >2 for women or >3 for men on the AUDIT-C

• at least 1 binged drinking episode in the prior 30 days

Exclusion Criteria:

• no cell phone with text messaging

• have been diagnosed with an alcohol or substance use disorder

• pregnant or planning pregnancy

• taking medicine for a psychiatric disorder (including depression, anxiety)

• taking any medicine that could interact with alcohol

Related Conditions & MeSH terms

• Alcohol Consumption
• Alcohol Drinking

Intervention

Behavioral:
• Drinking Cognition Feedback (DCF)
12 weeks of interactive text messaging focused on providing feedback related only to pre-weekend drinking cognitions (plans, desire to get drunk).
• Alcohol Risk Feedback (ARF)
12 weeks of interactive text messaging focused on providing feedback related only to post-weekend alcohol consumption (max drinks consumed on any occasion over the weekend).
• Adaptive Goal Support (AGS)
12 weeks of interactive text messaging focused on providing adaptive goal support (based on running average of max drinks consumed).
• COMBO
12 weeks of interactive text messaging incorporating features of DCF, ARF and AGS.

Locations

Country	Name	City	State
United States	University of Pittsburgh Medical Center Emergency Department	Pittsburgh	Pennsylvania

Sponsors (2)

Lead Sponsor	Collaborator
University of Pittsburgh	National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Number of Binge Drinking Days	Measured by the # days on the Timeline Followback Calendar that a male reported 5+ drinks or a female reported 4+ drinks	12 weeks after starting intervention
Secondary	Drinks Per Drinking Day	drinks per drinking day = mean drinks divided by the number of days with any alcohol consumption using the 30-day TLFB Calendar.	12 weeks after starting intervention
Secondary	Count of Participants With Any Binge Drinking Day	Using the Timeline Followback Calendar, any male participant reported one or more days with 5+ drinks or a female with one or more days with 4+ drinks are coded=1; otherwise participant is coded=0	12 weeks after starting intervention
Secondary	Brief Young Adult Alcohol Consequences Questionnaire Score	Brief Young Adult Alcohol Consequences Questionnaire (B-YAACQ). The B-YAACQ is a 24-item measure of alcohol- related problems that utilizes a dichotomous (present or absent) scoring format. Sum of items 1-48. Higher scores (count of items marked as 'present') on the B-YAACQ not only indicate a wider variety but also reflect a more severe pattern of alcohol-related problems.	12 weeks after starting intervention