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Albuminuria clinical trials

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NCT ID: NCT03504566 Withdrawn - Clinical trials for Diabetic Nephropathy Type 2

Rotation for Optimal Targeting of Albuminuria and Treatment Evaluation (ROTATE-2)

ROTATE-2
Start date: November 15, 2017
Phase: Phase 4
Study type: Interventional

This project is an intervention study where type 2 diabetic patients will rotate through 4 different albuminuria lowering drugs with the aim to 1) quantify the individual relationship between drug exposure and albumin lowering response of different albuminuria lowering drugs in type 1 and type 2 diabetics; and 2) to investigate the effect of the same drug intervention on the glycocalyx layer in blood vessels. The overall purpose of this study is to allow for future personalized treatment of diabetics with regards to treating kidney disease more effectively than current standardized strategies.