Airway Extubation Clinical Trial
Official title:
Diaphragmatic Shortening Fraction and Pulmonary Ultrasound Combined Analysis for Extubation Success Prediction in Critical Care Patients
NCT number | NCT02799056 |
Other study ID # | NM16-00003 |
Secondary ID | |
Status | Completed |
Phase | |
First received | |
Last updated | |
Start date | May 2016 |
Est. completion date | June 2017 |
Verified date | December 2018 |
Source | Hospital Universitario Dr. Jose E. Gonzalez |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
The primary objective is to assess whether the fraction of diaphragmatic shortening in combination with the presence / absence of alveolar-interstitial syndrome evaluated through chest ultrasound may predict successful extubation in adult patients hospitalized in the intensive care unit.
Status | Completed |
Enrollment | 82 |
Est. completion date | June 2017 |
Est. primary completion date | June 2017 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - 18 years of older - Hospitalized in medical or surgical intensive care unit - Successful spontaneous ventilation trial Exclusion Criteria: - Patients reintubated after a first failure after extubation - Injuries to prevent conduct ultrasound - Pregnancy - History of neuromuscular disease - Brain injury that prevented adequate protection of the airway (Glasgow Coma Scale <8) - Unilateral or bilateral Pneumothorax - Presence of chest tube in right hemothorax - Right subphrenic abscess - Known uni- or bilateral phrenic nerve injury - Unilateral or bilateral diaphragmatic Paralysis - Unwillingness of the patient or guardian to participate in the study |
Country | Name | City | State |
---|---|---|---|
Mexico | UANL University Hospital | Monterrey | Nuevo León |
Lead Sponsor | Collaborator |
---|---|
Hospital Universitario Dr. Jose E. Gonzalez |
Mexico,
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Huaringa AJ, Wang A, Haro MH, Leyva FJ. The weaning index as predictor of weaning success. J Intensive Care Med. 2013 Nov-Dec;28(6):369-74. doi: 10.1177/0885066612463681. Epub 2012 Oct 22. — View Citation
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Soummer A, Perbet S, Brisson H, Arbelot C, Constantin JM, Lu Q, Rouby JJ; Lung Ultrasound Study Group. Ultrasound assessment of lung aeration loss during a successful weaning trial predicts postextubation distress*. Crit Care Med. 2012 Jul;40(7):2064-72. doi: 10.1097/CCM.0b013e31824e68ae. — View Citation
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* Note: There are 17 references in all — Click here to view all references
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Extubation success | The investigators consider successful extubation when the patient does not require reintubation within 72 hours of its extubation | 72 h after extubation |
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