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Airway Control clinical trials

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NCT ID: NCT04924621 Recruiting - Airway Control Clinical Trials

Sedation Compaired With Anesthesia With THRIVE in Endotracheal Intubation With Difficult Airways

Start date: June 10, 2021
Phase: N/A
Study type: Interventional

To compare the difference in endotracheal intubation in participants with difficult airway between under general anesthesia by Transnasal Humidified Rapid-Insufflation Ventilatory Exchange and under traditional sedation by mask ventilation. The investigators focus on the different outcomes in oxygenation maintaince, carbon dioxide removal and the effectiveness of safety apnea time, to evaluate the safety of receiving endotracheal intubation under general anesthesia in participants with difficult airway.

NCT ID: NCT04100564 Recruiting - Trauma Injury Clinical Trials

LITES Task Order 0005 Prehospital Airway Control Trial (PACT)

PACT
Start date: April 1, 2021
Phase: N/A
Study type: Interventional

The Prehospital Airway Control Trial (PACT) is a proposed 5 year, open label, multi-center, stepped-wedge randomized trial comparing airway management strategies of prehospital trauma patients. The initial airway attempt will be randomized to either usual care (control) or a supraglottic airway management approach (intervention). The primary outcome will be 24 hour survival, with secondary outcomes to include survival to hospital discharge, expected clinical adverse events, airway management performance, ICU length of stay, ventilator days, incidence of ARDS, and incidence of ventilator associated pneumonia. Subjects will be enrolled across approximately 17 prehospital agencies at select LITES Network sites and will enroll a total of 2,009 subjects.

NCT ID: NCT04080440 Recruiting - Clinical trials for Mechanical Ventilation

Brain-injured Patients Extubation Readiness Study

Biper
Start date: February 9, 2020
Phase: N/A
Study type: Interventional

The BIPER study is a stepped wedge cluster randomised clinical trial aiming to decrease extubation failure in critically-ill brain-injured patients with residual impaired consciousness using a simple clinical score.