AIDS Clinical Trial
Official title:
Do CCR5 Antagonists Improve the Overall Survival of Patients With AIDS-related Progressive Multifocal Leucoencephalopathy?
Progressive multifocal leucoencephalopathy (PML) is a demyelinating disease caused by John
Cunningham virus (JCV) reactivation. Numerous molecules have been overstated because there
were inaccurately tested in non-rigorous clinical trial.
The objective is to draw lessons from repeatedly false hopes of unconfirmed PML treatments
that might contribute to prescribing ineffective drugs on claimed efficacy in case reports or
small series and by failing to respect the need for clinical trial evaluation before
authorizing their widespread use.
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