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Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT04202120
Other study ID # AFC2018
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date January 12, 2018
Est. completion date December 31, 2020

Study information

Verified date December 2019
Source The Hong Kong Polytechnic University
Contact Alma Au, PhD
Phone +85293609492
Email ssalma@polyu.edu.hk
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Memory performance is shown to be affected by age stereotypes among older adults. The purpose of the study is to examine the effects of age stereotype primes on episodic memory using priming intervention. The moderating effects of social participation is also examined.


Description:

All participants are community-dwelling older adults residing in Hong Kong. They are invited to review their social participation profile and given a brief psycho-education about memory.

They are then randomly allocated to one of the two following conditions. Participants are primed either with age stereotypes or non-age stereotypes words by implicit priming intervention in the context of a reaction task prior to the episodic memory tasks. Other measures such as demographic variables and social participation rate are collected by questionnaire during the delayed recall interval.


Recruitment information / eligibility

Status Recruiting
Enrollment 150
Est. completion date December 31, 2020
Est. primary completion date October 31, 2020
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 55 Years to 65 Years
Eligibility Inclusion Criteria:

Indication of largely normal cognitive functioning as screened on the Montreal Cognitive Assessment (MoCA) with Hong Kong norms -

Exclusion Criteria:

Sensory deficits and evidence of cognitive impairment as screened on the Montreal Cognitive Assessment (MoCA) with Hong Kong norms

-

Study Design


Related Conditions & MeSH terms


Intervention

Other:
Age-related stereotyping priming
The priming intervention was performed using the E-prime 2.0 software (Psychology Software Tools, Pittsburgh, PA). To ensure the primes flashed on screen were beyond awareness, the similar adjustment procedure was taken (see Levy, 1996; Stein et al., 2002). After the trial block, participants were asked to try to report any words viewed during each trial. The stimulus onset asynchrony (SOA) will be reduced or enhanced whenever 2 words or above were correctly reported or no single word could be reported respectively. The priming SOA for this study ranged from 32 ms to 208 ms (M = 98.70 ms. SD = 48.60).
Non age-related stereotype priming
he priming intervention was performed using the E-prime 2.0 software (Psychology Software Tools, Pittsburgh, PA). To ensure the primes flashed on screen were beyond awareness, the similar adjustment procedure was taken (see Levy, 1996; Stein et al., 2002). After the trial block, participants were asked to try to report any words viewed during each trial. The stimulus onset asynchrony (SOA) will be reduced or enhanced whenever 2 words or above were correctly reported or no single word could be reported respectively. The priming SOA for this study ranged from 32 ms to 208 ms (M = 98.70 ms. SD = 48.60).

Locations

Country Name City State
Hong Kong Applied Social Sciences, Hong Kong Polytechnic University Hong Kong

Sponsors (1)

Lead Sponsor Collaborator
The Hong Kong Polytechnic University

Country where clinical trial is conducted

Hong Kong, 

References & Publications (3)

Au A, Chan AS, Chiu H. Verbal learning in Alzheimer's dementia. J Int Neuropsychol Soc. 2003 Mar;9(3):363-75. — View Citation

Stein R, Blanchard-Fields F, Hertzog C. The effects of age-stereotype priming on the memory performance of older adults. Exp Aging Res. 2002 Apr-Jun;28(2):169-81. — View Citation

Wong A, Yiu S, Nasreddine Z, Leung KT, Lau A, Soo YOY, Wong LK, Mok V. Validity and reliability of two alternate versions of the Montreal Cognitive Assessment (Hong Kong version) for screening of Mild Neurocognitive Disorder. PLoS One. 2018 May 23;13(5):e0196344. doi: 10.1371/journal.pone.0196344. eCollection 2018. — View Citation

Outcome

Type Measure Description Time frame Safety issue
Primary Hong Kong List Learning Test The Hong Kong List Learning is a validated tool for assessing episodic memory for aged Chinese speaking adults (Chan, 2006). It was further taken for investigating differences among older adults with normal cognitive ability and older adults with mild cognitive impairment (Yeung et al., 2016). The random control list was taken in this study. It comprises 16 words formed by four categories: Change from baseline through study completion, an average of 2 hours
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