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Neurokinin (NK) 1 Antagonist for Pathological Aggression for Harmful, Impulsive, and Self-/Aggressive Behaviour — AHIMSA-1  

Aggression Clinical Trial

Official title:
NK1 Antagonists for Pathological Aggression: A Protocol for Harmful, Impulsive, and Self-/Aggressive Behavior (AHIMSA-1) Trial

Clinical Trial Summary

Neurokinin (NK) -1 antagonist will be administered to study patients in a double-blind placebo trial. Patients receive assessments including Anger Disorder Scale (ADS) and Modified Overt Aggression Scale (MOAS) and perform computerized study tasks during MRI before the trial begins. Patients receive either one week of the drug or one week of placebo and perform the same tasks and assessments. Then patients receive another week of the alternate pill, followed by another round of tasks during MRI and assessments.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02989779
Study type Interventional
Source St. Joseph's Healthcare Hamilton
Contact Sheila Verhage-Brown, MD
Phone 905-522-1155
Email sverhage@stjoes.ca
Status Recruiting
Phase Phase 1/Phase 2
Start date January 2017
Completion date June 2020
View Details
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