To Investigate the Influence of Surgery and Anesthesia on Elderly Population by Using the Comprehensive Geriatric Assessment

Aged Clinical Trial

— CGA  

Official title:

To Investigate the Influence of Surgery and Anesthesia on Elderly Population by Using the Comprehensive Geriatric Assessment

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04042064
• Other study ID #: 201900881B0
• Status: Recruiting
• Start date: August 1, 2019
• Est. completion date: June 30, 2021

Study information

• Verified date: July 2019
• Source: Chang Gung Memorial Hospital
• Contact: Hung-Jr Chiou, M.D.
• Phone: 886-3-3281200
• Email: ma5372[@]cgmh.org.tw
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Aging is a universal and progressive physiological phenomenon clinically characterized by degenerative changes in both the structure and the functional capacity of organs and tissues. A comprehensive geriatric assessment (CGA) has now become a standard assessment for caring for the elderly. CGA is a multidisciplinary team with the goal of improving the overall well-being of the elderly. It encompasses screening, diagnosis and treatment of the elderly. In this study, we use the comprehensive geriatric assessment to study the effects of surgery and anesthesia on elderly patients.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 2000
• Est. completion date: June 30, 2021
• Est. primary completion date: July 1, 2020
• Gender: All
• Age group: 60 Years and older

Eligibility

Inclusion Criteria:

• Participant is willing and able to give informed consent for participation in the study.

• Participants receiving general anesthesia for longer than 1 hour.

Exclusion Criteria:

• Participants receiving local anesthesia.

• Participants receiving regional anesthesia.

• Participants receiving general anesthesia for less than 1 hour.

• Participants with psychiatric disorder.

Related Conditions & MeSH terms

• Aged
• Comprehensive Geriatric Assessment
• Surgery and Anesthesia on Elderly

Locations

Country	Name	City	State
Taiwan	Chang Gung Memorial Hospital	Taipei

Sponsors (1)

Lead Sponsor	Collaborator
Chang Gung Memorial Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Mini-Mental Status Examination	The Mini-Mental Status Examination is a screening tool for dementia. The investigator asks the patient a series of questions to which the patient answers to his or her best ability.; Minium score of zero and a maximum score of 30. Lower value represents a worse outcome.; A score of less than 24 is considered abnormal.	Before general anesthesia till 48-hours post-anesthesia.
Primary	Geriatric Depression Scale - 15	The Geriatric Depression Scale (short form) is a screening tool for depression. It is a questionnaire composed of 15 questions. The investigator asks the patient 15 questions in which the patient answers "yes" or "no".; Each question weighs 1 point with a minimum score of zero and maximum score of 15.; The higher the score, the more likely depression is present. A score of 0 to 5 is normal. A score greater than 5 suggests depression.	Before general anesthesia till 48-hours post-anesthesia.
Primary	Confusion Assessment Method	The Confusion Assessment Method is a screening tool for delirium. It comprises of four parts: "(1) acute onset and fluctuating course", "(2) inattention", "(3) disorganized thinking", and "(4) altered level of consciousness".; "(1) Acute onset and fluctuating course" has two questions and the rest with one question each.; The investigator conducts the assessment with the patient answering "yes" or "no" to each question.; Delirium is diagnosed under these scenarios: yes to all four questions, yes to (1)+(2)+(3), yes to (1)+(2)+(4).	Before general anesthesia till 48-hours post-anesthesia.
Primary	Barthel Index	Barthel Index is an ordinal scale used to measure performance in ADL (activities of daily living).; It comprises of ten variables describing ADL. A minium of zero and a maximum and 100 is scored. Higher score reflects greater ability to function independently. 60 or less is classified as dependent. Scores of 0-20 indicate "total" dependency, 21-60 indicate "severe" dependency, 61-90 indicate "moderate" dependency, and 91-99 indicates "slight" dependency	Before general anesthesia till 48-hours post-anesthesia.