Assessment of Physical Performance After Oral Supplementation of Magnesium in a Sample of Old Women in Good Health

Age Related Muscle Loss Clinical Trial

— Magnesium  

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01971424
• Other study ID #: 2011491
• Status: Completed
• Phase: N/A
• First received: October 23, 2013
• Last updated: October 23, 2013
• Start date: January 2012
• Est. completion date: March 2013

Study information

• Verified date: October 2013
• Source: University of Padova
• Contact: n/a
• Is FDA regulated: No
• Health authority: Italy: National Bioethics Committee
• Study type: Interventional

Clinical Trial Summary

Magnesium deficiency is associated also in the elderly with low physical performance; nevertheless trials about the effect of supplementation of magnesium on physical performance are not available in old people. The aim of our study is to investigate whether 12-weeks of oral magnesium supplementation improves physical performance in healthy elderly women

Recruitment information / eligibility

• Status: Completed
• Enrollment: 100
• Est. completion date: March 2013
• Est. primary completion date: March 2013
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 65 Years and older

Eligibility

Inclusion Criteria:

• People over 65 years, not residents in nursing home, in good health

Exclusion Criteria:

• previous supplementation of calcium, potassium or magnesium

• use of pump proton inhibitors or digitalis

• important co-mordidities such renal failure

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Age Related Muscle Loss

Intervention

Dietary Supplement:
• Mg oxide

Other:
• healthy diet

Locations

Country	Name	City	State
Italy	Geriatrics Division, Department of Medicine	Padova

Sponsors (1)

Lead Sponsor	Collaborator
University of Padova

Country where clinical trial is conducted

Italy, 

References & Publications (1)

Dominguez LJ, Barbagallo M, Lauretani F, Bandinelli S, Bos A, Corsi AM, Simonsick EM, Ferrucci L. Magnesium and muscle performance in older persons: the InCHIANTI study. Am J Clin Nutr. 2006 Aug;84(2):419-26. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Changes in short physical performance battery (SPPB)		Baseline and after 12 weeks	No
Secondary	Changes in appendicular skeletal mass (ASMMI)		Baseline and after 12 weeks	No