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Clinical Trial Summary

This interventional study is a single-center, open label, 26-week study, designed to evaluate the safety and treatment efficacy of K8 in patients with geographic atrophy (GA) due to age-related macular degeneration (AMD). Up to 5 subjects will receive study medication. Study treatment will be administered by intravitreal injections. Participants will have 7 scheduled visits - Screening with baseline (injection), safety visit 2 days after injection, week 4, week 13 (injection), safety visit 2 days after injection, week 17, week 26. Exams will look for continuous changes in visual acuity, change in area of geographic atrophy lesions in diagnostic imaging, response measured by multifocal electroretinogram, change in reading speed, and change in microperimetry response.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06164587
Study type Interventional
Source University of Kentucky
Contact Sara Kuhl
Phone 859-562-3570
Email sara.kuhl@uky.edu
Status Recruiting
Phase Phase 1
Start date April 18, 2024
Completion date April 2025

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