Age Related Macular Degeneration Clinical Trial
Official title:
Comparison of Treatment Response to Intravitreal Injection of Combined Propranolol and Bevacizumab Versus Bevacizumab Monotherapy in Patients With Wet Age Related Macular Degeneration :A Clinical Trial
This study is designed to compare the effect of combined intravitreal Bevacizumab and
Propranolol injection versus Bevacizumab monotherapy in patients with Age Related Macular
Degeneration.
Methods:
In this study patients with Age Related Macular Degeneration who are naïve or had history of
previous treatment are included. The eligible patients in randomized in two groups
"Bevacizumab" and "Bavacizumab + propranolol" and in injected intravitreally for 3 times
monthly. In "Bevacizumab+propranolol" group patients receive two injections at each session
Bavacizumab and propranolol. In "Bevacizumab" group patients receive only Bevacizumab. The
patients are followed for 6 months and central macular thickness and visual acuity is
measured at baseline and monthly for 6 month. Baseline ancillary exams include Fluorescein
Angiography and OCT-Angiography which is performed at the final exam as well. Patients
needing any therapeutic intervention is addressed during the 6 month follow up period.
n/a
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