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Bevacizumab Versus Ranibizumab in Age Related Macular Degeneration — AxL-2009  

Age Related Macular Degeneration Clinical Trial

Official title:
Comparative Study - Bevacizumab Versus Ranibizumab in Age Related Macular Degeneration

Clinical Trial Summary

To report the short term anatomic and visual acuity response after intravitreal injection of bevacizumab and ranibizumab in patients with choroidal neovascularization secondary to age-related macular degeneration.

Clinical Trial Description

We conducted a retrospective study of 500 eyes with choroidal neovascularization secondary to age-related macular degeneration who were treated with at least two (initial and one month after) intravitreal injection of 1.25 mg bevacizumab or 0.5 mg ranibizumab and had a follow-up of at least 3 months. Patients underwent Snellen visual acuity testing, optical coherence tomography (OCT) imaging and ophthalmoscopic examination at baseline and follow-up visits. ;

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01014468
Study type Interventional
Source Instituto de Olhos de Goiania
Contact
Status Active, not recruiting
Phase Phase 3
Start date March 2009
Completion date February 2012
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