Detection of Topographic Residual Acuity in Patients With Age Related Macular Degeneration

Age-Related Macular Degeneration Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00329277
• Other study ID #: SNM200601
• Status: Completed
• Phase: N/A
• First received: May 23, 2006
• Last updated: May 22, 2008
• Start date: April 2006
• Est. completion date: January 2008

Study information

• Verified date: November 2006
• Source: University Health Network, Toronto
• Contact: n/a
• Is FDA regulated: No
• Health authority: Canada: Health Canada
• Study type: Interventional

Clinical Trial Summary

Standard perimetry provides information on topographical retinal sensitivity to light stimuli, however the said locus is not necessarily the preferred locus for fixation. Standard perimetry could also be used as a way for macular scotoma mapping, indirectly showing the fixation locus. Topographic acuity at the preferred retinal locus can be determined if correlation between loci with high sensitivity, eccentric fixation loci and potential visual acuity measurements are correlated.

PURPOSE OF THE STUDY:

Determination of visual acuity at preferred retinal locus in Low Vision patients with ARMD using eye standard automated and computerized perimetry methods.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 30
• Est. completion date: January 2008
• Est. primary completion date: January 2008
• Accepts healthy volunteers: No
• Gender: Both
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• AMD with documented pathology

• Low Vision both eyes

• BCVA 20/50-20/400 in best eye

Exclusion Criteria:

• Cognitive impairment

• Other retinal pathology

• Previous retinal surgery

• Significant media opacity

Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

• Age-Related Macular Degeneration
• Macular Degeneration

Intervention

Procedure:
• perimetry

Locations

Country	Name	City	State
Canada	Dr S N Markowitz	Toronto	Ontario

Sponsors (1)

Lead Sponsor	Collaborator
University Health Network, Toronto

Country where clinical trial is conducted

Canada, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Location of eccentric retinal locus of highest fixation accuracy
Secondary	Location of eccentric locus with best retinal sensitivity