Study of the Aerosol Deposition With Vented and Unvented Jet Nebulizer in Healthy Subjets

Aerosol Drug Therapy Clinical Trial

Status Recruiting

Clinical Trial Summary

Open-vent jet nebulizers are frequently used to promote drug lung deposition but their clinical efficacy and indications are not clear.

Our study aimed to compare inhaled mass, and lung deposition of amikacin by using a jet nebulizer (Sidestream) under two different configurations: vented and unvented coupled to a 110 ml corrugated piece of tubing.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Pharmacokinetics Study, Intervention Model: Parallel Assignment, Masking: Open Label

Related Conditions & MeSH terms

• Aerosol Drug Therapy

• NCT number: NCT01428323
• Study type: Interventional
• Source: Cliniques universitaires Saint-Luc- Université Catholique de Louvain
• Contact: Laurent NP Pitance, PT
• Phone: +3227645711
• Email: laurent.pitance@uclouvain.be
• Status: Recruiting
• Phase: N/A
• Start date: January 2011
• Completion date: September 2011