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6% Hydroxyethyl Starch (130/0.4) Coload for Postspinal Anesthesia Hypotension

Adverse Effect Clinical Trial

Official title:
6% Hydroxyethyl Starch (130/0.4) Coload for Postspinal Anesthesia Hypotension in Patients Undergoing Caesarean Section: A Randomized Sequential Allocation Dose-finding Study

Clinical Trial Summary

The purpose of this study is to investigate the ED50 and ED90 for an effective 6% Hydroxyethyl starch (130/0.4) coload infusion dose for postspinal anesthesia hypotension in patients undergoing cesarean section.

Clinical Trial Description

Post-spinal anesthesia hypotension is a frequent complication during spinal anesthesia for cesarean section. The incidence of post-spinal anesthesia hypotension is as high as 62.1-89.7% if prophylactic measures are not taken. Colloid fluid coload has been highly demonstrated for prevention and/or treatment of post-spinal anesthesia hypotension. However, the ED50 and ED90 for an effective 6% Hydroxyethyl starch (130/0.4) coload infusion dose for postspinal anesthesia hypotension are still unknown. The purpose of this study is to investigate the ED50 and ED90 for an effective 6% Hydroxyethyl starch (130/0.4) coload infusion dose for postspinal anesthesia hypotension in patients undergoing cesarean section. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05475886
Study type Interventional
Source General Hospital of Ningxia Medical University
Contact Yi Chen, M.D.
Phone 86-951-674-3252
Email czzyxgp@163.com
Status Recruiting
Phase N/A
Start date February 1, 2024
Completion date April 21, 2024
View Details
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