Study of SGR-3515 In Participants With Advanced Solid Tumors.

Status Not yet recruiting

Clinical Trial Summary

The purpose of this study is to learn about the effects of a new study drug, called SGR-3515 that may be a treatment for advanced solid tumors.

Clinical Trial Description

SGR-3515-101 is a phase 1, fist-in-human, single agent, dose-escalation study designed to evaluate the safety, tolerability, dose limiting toxicities, pharmacokinetics, pharmacodynamics, and preliminary anti-tumor activity of SGR-3515 and to identify the maximum tolerated dose, recommended phase 2 dose and schedule of SGR-3515, in participants with advanced solid tumors hypothesized to be sensitive to Wee1/Myt1 inhibition and any solid tumors with designated molecular perturbation relevant to DNA damage repair pathway, including but not limited to CCNE1 amplification. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06463340
Study type	Interventional
Source	Schrödinger, Inc.
Contact	Study Physician
Phone	+15032991150
Email	sdgr-trials-group@schrodinger.com
Status	Not yet recruiting
Phase	Phase 1
Start date	June 24, 2024
Completion date	December 31, 2026

View Details

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