A Phase I Study of RGT-264 in Subjects With Advanced Solid Tumors

Status Active, not recruiting

Clinical Trial Summary

This is a Phase 1 dose escalation and dose expansion study to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of RGT-264 as monotherapy in subjects with advanced solid tumors.

Clinical Trial Description

This first-in-human (FIH) study of RGT-264 will evaluate safety, pharmacokinetics (PK) and efficacy of RGT-264 in subjects with advanced solid tumors. The primary objective is to determine the maximum tolerated dose (MTD)/maximum administered dose (MAD) and the recommended phase II dose (RP2D) of RGT-264 as monotherapy, and to evaluate the safety and tolerability of RGT-264. The secondary objectives include the assessments of PK profile and preliminary efficacy of RGT-264. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05764915
Study type	Interventional
Source	Regor Pharmaceuticals Inc.
Contact
Status	Active, not recruiting
Phase	Phase 1
Start date	February 15, 2023
Completion date	August 2, 2025

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