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A Phase I Study, Evaluating the Safety, Pharmacokinetics and Efficacy of PRJ1-3024 in Subjects With Advanced Solid Tumors

Advanced Solid Tumor Clinical Trial

Official title:
A Phase I, First-In-Human, Open-Label Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of PRJ1-3024 in Subjects With Advanced Solid Tumors

Clinical Trial Summary

This is a Phase I, multicenter, open-label, 3+3 dose escalation study to determine the safety and preliminary efficacy of PRJ1-3024 in subjects with relapsed/refractory solid tumors.

Clinical Trial Description

The study will evaluate the safety, tolerability, PK, and pharmacodynamics of PRJ1-3024 and will determine the maximum tolerated dose in subjects with advanced solid tumors. PRJ1-3024 will be evaluated as an oral therapeutic that tests the anti-tumor activity of PRJ1-3024 in patients with solid tumors and has not yet been tested in humans. This study will find the safe and tolerable recommended dose in subjects with advanced solid tumors as a open-label, 3+3 dose escalation study. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05159700
Study type Interventional
Source Zhuhai Yufan Biotechnologies Co., Ltd
Contact Yang Xu
Phone 8054905672
Email yang.xu@ming-med.com
Status Recruiting
Phase Phase 1
Start date March 31, 2022
Completion date August 15, 2024
View Details
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