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A Study of MRG002 in the Treatment of Patients With HER2-positive Advanced Solid Tumors

Advanced Solid Tumor Clinical Trial

Official title:
A Phase I, Open-label, Multi-center, First in Human, Dose Escalation and Expansion Study to Assess the Safety, Tolerability, Efficacy and Pharmacokinetics of MRG002 in Patients With HER2 Positive Advanced Solid Tumors

Clinical Trial Summary

The objective of this study is to assess the safety, efficacy, pharmacokinetics, and immunogenicity of MRG002 in patients with HER2-positive advanced solid tumors.

Clinical Trial Description

This study consists of two parts. Phase Ia is a dose escalation study to determine the maximum tolerated dose (MTD) and recommended phase II dose (RP2D) of MRG002. Phase Ib is a dose expansion study to further assess the efficacy and safety of MRG002 at confirmed RP2D. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04941339
Study type Interventional
Source Shanghai Miracogen Inc.
Contact Program Director
Phone 86-21-61637960
Email clinicaltrials@miracogen.com.cn
Status Recruiting
Phase Phase 1
Start date November 21, 2018
Completion date October 2022
View Details
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