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Safety and Efficacy of DCB-BO1301 in Advanced Melanoma

Advanced Melanoma Clinical Trial

Official title:
An Open-Label Phase I/IIa Dose-Escalation Study Evaluating the Safety, Tolerability and Efficacy of DCB-BO1301 as Add-on Therapy to Dacarbazine in Subjects With Advanced Melanoma

Clinical Trial Summary

The primary study objectives are 1. to evaluate the safety and tolerability profiles of DCB-BO1301 and to determine the maximum tolerated dose (MTD) of DCB-BO1301 as add-on therapy to dacarbazine in subjects with advanced melanoma (Phase I) 2. to evaluate the efficacy profile of DCB-BO1301 at MTD or lower dose level as add-on therapy to dacarbazine in subjects with advanced melanoma in terms of progression free survival (Phase IIa)

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02994498
Study type Interventional
Source Chung Mei Biopharma Co., Ltd
Contact Leon YZ Zhan, MS
Phone +886-4-2329-0578
Email Leon.Zhan@cm-biopha.com
Status Not yet recruiting
Phase Phase 1/Phase 2
Start date March 2023
Completion date December 2025
View Details
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