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Effect of Fluconazole on PK of Fluzoparib in Healthy Male Subjects

Advanced Cancer Clinical Trial

Official title:
Study on the Pharmacokinetics of Fluconazole on Single-center, One-arm, Open and Fixed Sequences of Fluzoparib in Healthy Male Subjects

Clinical Trial Summary

The purpose of this study is to evaluate the Effect of fluconazole on the Pharmacokinetics of Fluzoparib in Healthy male Adults

Clinical Trial Description

Subjects received oral Fluzoparib 20 mg after D1 single meal, D2-D4 for washing period, D5 started oral fluconazole 400 mg/day/day after meal, continuous administration for 6 days to D10, D8 meal After oral administration of fluconazole 400 mg, a single oral dose of Fluzoparib 20 mg was given immediately. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04193319
Study type Interventional
Source Jiangsu HengRui Medicine Co., Ltd.
Contact
Status Completed
Phase Phase 1
Start date July 19, 2019
Completion date September 12, 2019
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