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NCT00387491 Clinical Trial

Dose Ranging Study in Healthy Methadone Maintenance Subjects

Adult Clinical Trial

Official title:
A Randomized, Double-blind, 4-period Crossover, Dose-ranging Study to Determine the Effects on the Oral-cecal Transit Time of Single Doses of MOA-728 and the Safety and Tolerability of Multiple Doses of MOA-728 in Stable Methadone Maintenance Subjects

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00387491
Other study ID # 3200A3-102
Secondary ID
Status Completed
Phase Phase 1
First received
Last updated
Start date June 2006
Est. completion date October 2006

Study information
Verified date November 2019
Source Bausch Health Americas, Inc.
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

To assess the effect of a single oral dose of MOA-728, an investigational drug, on the oral-cecal transit time in subjects who are taking methadone.

Recruitment information / eligibility
Status Completed
Enrollment 16
Est. completion date October 2006
Est. primary completion date October 2006
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 65 Years
Eligibility 1. Men or nonlactating and nonpregnant women, aged 18 to 65 years

2. Healthy as determined by the investigator on the basis of medical history, physical examination, clinical laboratory test results, vital signs, and 12-lead electrocardiogram

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• MOA-728

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Bausch Health Americas, Inc.

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Oral-cecal transit time will be evaluated.
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