the Individualized Stepwise Treatment Mode of Adolescent Idiopathic Scoliosis

Adolescent Scoliosis Clinical Trial

Official title:

the Individualized Stepwise Treatment Mode of Adolescent Idiopathic Scoliosis Based on Transformer Learning Algorithm

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06314594
• Other study ID #: 2024KY920
• Status: Recruiting
• Phase: N/A
• Start date: December 20, 2023
• Est. completion date: December 1, 2026

Study information

• Verified date: March 2024
• Source: Hangzhou Medical College
• Contact: Xinyun Dr LI, Doctor
• Phone: 8618069783240
• Email: lxyjasmine2010[@]163.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Based on the risk factors affecting adolescent scoliosis found in the previous social survey, this project adopts the paradigm based on transfer learning and semi-supervised learning, and uses mathematical methods such as multiple learning methods and Transformer image classification algorithms to develop and verify the early warning model and stepped treatment model of adolescent scoliosis, and conducts cost-effect analysis.

Description:

This study intends to build a standard system for the prevention and treatment of scoliosis in adolescents, do a good job in school health education and prevention and control work in school, comprehensively strengthen the construction of the prevention and control system of spondylosis, improve the ability of professionals in medical institutions, and give full play to the role of home-school-medical in the prevention and control of abnormal spinal curvature in children Firstly, relying on the investigation report, we independently develop the software platform and physical device for measuring, preventing and correcting scoliosis. Secondly, we use a series of prevention and control advantages to change from passive to active. Based on the Internet and big data technology, we integrate Western medicine data management and monitoring technology to establish the characteristics of the disease General disease information (personal history, family history, solar terms, climate and environment detection indicators, etc.) as one of the health management platform, the management platform set up health archives disease risk early warning health intervention and health promotion education follow-up management system management data quality control review data analysis and visualization 9 modules, respectively set up a management platform patient-side physician side and management background 3 parts through sampling investigation clinical research, break the medical school barriers, to build a personalized step treatment model for adolescent scoliosis.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 76
• Est. completion date: December 1, 2026
• Est. primary completion date: December 1, 2025
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 3 Years to 18 Years

Eligibility

Inclusion Criteria:

• Diagnosis of moderate to mild scoliosis (Cobb angle less than 45°), age 12-16 years, male or female, no psychiatric illness, normal communication, reading and writing

Exclusion Criteria:

• Patients with a clear history of triggers, such as diseases caused by trauma, surgery, etc., cognitive dysfunction, severe heart, liver, kidney and other organ dysfunction, malignant tumors, immune diseases and other malignant diseases

Related Conditions & MeSH terms

• Adolescent Scoliosis
• Scoliosis

Intervention

Procedure:
• Conventional treatment
Routine medical treatment mode and routine treatment plan, observation and intervention for 4 months.

Behavioral:
• intervention treatment
Individualized step-by-step treatment model, after screening, the results are imported into the health management platform, and the optimal plan is obtained through data calculation, which is sent to the individual (family) or school, and corresponding treatment is carried out under the guidance of the platform, and observation and intervention 4 months.

Locations

Country	Name	City	State
China	the Affiliated Zhejiang Provincial People's Hospital to Hangzhou Medical College.	Hangzhou	Zhejiang

Sponsors (1)

Lead Sponsor	Collaborator
Hangzhou Medical College

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Number of Cobb angles	X-rays were used to check the number of Cobb angles before and 4 months after the intervention to observe the improvement of scoliosis	4 months before the intervention and 4 months after the intervention
Primary	Accuracy of new screening modalities	The new screening method "general examination + forward flexion test + scoliosis measuring instrument" was used for examination, and the data results before and 4 months after intervention were compared with the X-ray examination results to verify its accuracy.	4 months before and after the intervention, 4 months after the end of the intervention, and 8 months after the end of the intervention
Primary	Hamilton Depression Volume	Depression status was rated using the Hamilton Depression Rating Scale	4 months before and after the intervention, 4 months after the end of the intervention, and 8 months after the end of the intervention