Adolescent Idiopathic Scoliosis Clinical Trial
Official title:
Pilot Study of Functional and Morphometric Brain Abnormalities Related to Adolescent Idiopathic Scoliosis (MOR-FO-SIA)
Adolescent idiopathic scoliosis (AIS) is a complex deformity with different curves. These
different curves may be distinguished by different physiopathologic mechanisms.
Without fully convincing model of the emergence and development of AIS, their multifactorial
nature seems evident. Several pathophysiological theories involving the central nervous
system have been proposed: the AIS would be associated with disturbances of proprioceptive
or sensory perception, and/or with integration of this information. This would result in an
abnormal body image, responsible for sensorimotor asymmetry that may promote or cause the
deformation.
The Main aim of this study is to find cortical and subcortical morphometric differences in
the most common population of AIS (right thoracic AIS) compared to healthy adolescent
control girls.
Secondary Objectives are to study the cerebral white matter of the same groups (fractional
anisotropy in the main white matter tracts), and activation of sensorimotor neural networks
(fMRI activation and functional brain connectivity).
Abnormalities of the studied parameters may be used as biomarkers for AIS diagnosis and
classification.
n/a
Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT03935295 -
Dysport ® as an Adjunctive Treatment to Bracing in the Management of Adolescent Idiopathic Scoliosis
|
Phase 4 | |
Recruiting |
NCT06262269 -
Interest of Adapted Physical Activity by Tele-rehabilitation in Chronic Pathology - Idiopathic Scoliosis in Adolescents
|
N/A | |
Not yet recruiting |
NCT06003010 -
Yoga for Adolescent Idiopathic Scoliosis (AIS) Patients
|
N/A | |
Withdrawn |
NCT02590380 -
Comparing Pedicle Screw Systems for the Treatment of Adolescent Paediatric Spine Deformity
|
N/A | |
Completed |
NCT05669859 -
Efficacy of Postoperative Telerehabilitation in Adolescent Idiopathic Scoliosis
|
N/A | |
Completed |
NCT05242601 -
Investigation of Quality of Life in Adolescent Idiopathic Scoliosis
|
||
Recruiting |
NCT05919459 -
Effectiveness of Acceptance and Commitment Therapy Versus Active Controls in Improving Psychological Functions of Parents and Children With Adolescent Idiopathic Scoliosis: A Randomized Controlled Trial
|
N/A | |
Recruiting |
NCT05969301 -
Memory and Scoliosis Spinal Exercises
|
||
Enrolling by invitation |
NCT05790031 -
Trials of Intelligent Nighttime Brace With Smart Padding to Treat of Adolescent Idiopathic Scoliosis
|
N/A | |
Active, not recruiting |
NCT04867148 -
The Prediction and Prevention of Disease by Using Big Data in Motion Analysis
|
N/A | |
Completed |
NCT05056363 -
The Effects of Core Stability Training in Children With Adolescent Idiopathic Scoliosis
|
N/A | |
Completed |
NCT00989495 -
Comprehensive Cohort Study of Bracing for Adolescent Idiopathic Scoliosis (AIS): A Feasibility Study
|
N/A | |
Withdrawn |
NCT00958373 -
Risk Factors for Psychiatric Disorders Associated With Adolescent Idiopathic Scoliosis
|
N/A | |
Recruiting |
NCT05730920 -
IV Methadone vs EXPAREL Erector Spinae Plane Blockade in Pediatric Subjects Undergoing Idiopathic Scoliosis Correction
|
Phase 4 | |
Recruiting |
NCT03292601 -
Brace Monitoring for Adolescent Idiopathic Scoliosis (AIS)
|
N/A | |
Completed |
NCT04421157 -
Exercises in Adolescent Idiopathic Scoliosis
|
N/A | |
Completed |
NCT05127902 -
Association Between Postural Balance and Muscle Activity of the Lumbar and Lower Limb Muscles in Female With or Without Adolescent Idiopathic Scoliosis (AIS) During Standing Balance Tasks With Upper Limb Movement
|
||
Completed |
NCT05703737 -
Respiratory Function and Respiratory Muscle Strength in Adolescent Idiopathic Scoliosis
|
||
Completed |
NCT04092335 -
Evaluation of Adam's Forward Bend Test and Smartphone Application in Screening of Adolescent Idiopathic Scoliosis
|
||
Withdrawn |
NCT04877236 -
Green Sun Medical Dynamic Brace
|
N/A |