Adherence Clinical Trial
Official title:
Motivational Enhancement Therapy to Reduce Risk Behaviors in HIV Infected Youth
The purpose of this study is to conduct a pilot study of Motivational Enhancement Therapy
(MET), an empirically validated behavioral change strategy, with young adults who are HIV +.
The aim is to determine if MET is effective in increasing general health promotion
behaviors, adherence to HIV+ specific medical treatment over and above taking medication,
and decreasing risky behaviors in young adults who are HIV positive. The longer-term
objective is to identify and way to decrease HIV transmission rates, disease progression,
illness episodes, and hospitalizations in this high-risk population.
Hypotheses: 1)Youth receiving the motivational intervention plus referrals will report
greater reductions in risky behaviors than youth in the control group receiving standard
care plus referrals at 3-months post-baseline. This hypothesis will first be tested in the
whole sample using an overall risk index. Then, the hypothesis will be tested with each
behavior (reduced drug and alcohol use, condom use, taking medications,) within the
subgroups reporting problem levels of that behavior; 2)Youth in the intervention group will
demonstrate improved viral loads, will report greater improvement in perceived health
status, depression, general psychological distress, disclosure to sexual partners, and will
demonstrate greater attendance of medical and support service appointments than youth in the
control group at 3 months post-baseline; 3)Youth in the intervention group will report
greater reductions in temptation to engage in risky behaviors, increased self-efficacy, and
improvements in readiness to change their behavior than youth in the control group at 3
months post-baseline; 4)The differences between the intervention and control group from pre-
to post- intervention will be maintained at 6, 9, 12, and 15 months post-baseline (3, 6, 9,
and 12 months after intervention completion).
Status | Unknown status |
Enrollment | 60 |
Est. completion date | August 2005 |
Est. primary completion date | |
Accepts healthy volunteers | No |
Gender | All |
Age group | 16 Years to 24 Years |
Eligibility |
Inclusion Criteria: - A sample of 60 HIV+youth, ages 16-24, will be recruited from the four health care sites in the Michigan Title IV Project. Exclusion Criteria: - In order to increase the likelihood that the current intervention will be easily transportable to real world settings, exclusion criteria are kept to a minimum. No exclusions will be made due to co-morbid mental health problems ( i.e. ADHD, conduct disorder, depression, anxiety disorder), with the exception of thought disorder (i.e. schizophrenia, autism). It is assumed that severe psychosis in conjunction with HIV may require management strategies beyond the scope of the MET interventions (i.e. residential placement). As resources are not available in the current grant to hire and train therapists who are bilingual or translate study questionnaires/measures, subjects will required to speak English fluently. Hispanic or Arabic families who meet this criterion will be included in the study. Currently, all clients at the clinic sites meet this last criterion. |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
United States | Detroit Medical Center-CHM and UHC | Detroit | Michigan |
Lead Sponsor | Collaborator |
---|---|
National Institute on Drug Abuse (NIDA) | Wayne State University |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Reduction of Risk Behaviors (Sexual, Drug, & Health), Viral Burden & CD4+ T Cell Count | |||
Secondary | SES, health beliefs, physical and mental status, self-efficacy, stages of change, service utilization, HIV stigma |
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