Adherence to Medication Regime Clinical Trial
Official title:
The Influence of Once-daily Versus Twice-daily Immunosuppressive Regimen on Drug Compliance in Patients After Renal Transplantation
The main objective of this study was to compare the drug compliance in patients after renal
transplantation under once or twice-daily tacrolimus-based immunosuppressive regimen.
The rationale for this study is to access the influence of once-daily prolonged-release
tacrolimus versus standard twice-daily tacrolimus on drug compliance in renal transplantation
recipients base on the assumption that once-daily dosing regimen may help to improve drug
compliance.
This study will be a prospective, two-arm randomized and open-label, phase IV study to
compare the drug compliance in patients under prolonged-release once-daily tacrolimus versus
standard twice-daily tacrolimus based regimen after de novo renal transplantation.
The investigators will evaluate the drug compliance of the patients under once or twice-daily
tacrolimus-based regimen using the medication scale BAAIS® (basal assessment of adherence
with immunosuppressive medication scale)
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