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An Exploratory Trial of AZD3480 (TC-1734) for the Treatment of Adult Attention-Deficit/Hyperactivity Disorder (ADHD)

ADHD Clinical Trial

Official title:
An Exploratory Trial of AZD3480 (TC-1734) for the Treatment of Adult Attention-Deficit/Hyperactivity Disorder (ADHD)

Clinical Trial Summary

A 3-way cross-over trial of two weeks of treatment with three drug conditions. AZD3480 will be given in doses of (A) 5mg/day, (B) 50 mg/day and (C) placebo to 24 non-smoking adults with DSM-IV confirmed ADHD. Three week washout between each treatment period. CYP2D6 genotyping will be completed at screening and slow metabolisers will be excluded from participation in this study. Cognitive, ADHD symptom, safety and pharmacokinetic (PK) assessments will be made during each treatment period. Safety and tolerability assessments will be a major component of the trial and all serious adverse events (SAE) will be immediately (within 24 hours) reported to both Targacept and to AstraZenca.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

  • ADHD
  • Attention Deficit Disorder with Hyperactivity
Clinical Trial Details
NCT number NCT00683462
Study type Interventional
Source AstraZeneca
Contact
Status Completed
Phase Phase 2
Start date May 2008
Completion date July 2009
View Details
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