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Clinical Trial Summary

This is a randomized, controlled, open-label, multicenter study to evaluate the safety, tolerability, pharmacokinetic (PK), and adenovirus (AdV) antiviral activity of multiple ascending doses of IV brincidofovir (BCV). Approximately 30 eligible subjects will be sequentially enrolled into 1 of 3 planned cohorts. Within each cohort, subjects will be randomized in a 4:1 ratio to receive IV BCV dosed twice weekly (BIW) (on Days 1, 4, 8, and 11) or to receive investigator-assigned standard of care (SoC).


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03532035
Study type Interventional
Source Chimerix
Contact
Status Withdrawn
Phase Phase 2
Start date December 15, 2018
Completion date May 10, 2019

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