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A Study Of AL101In Patients With Adenoid Cystic Carcinoma (ACC) Bearing Activating Notch Mutations — ACCURACY  

Adenoid Cystic Carcinoma Clinical Trial

Official title:
A Phase 2, Open-Label, Multi-center Study of AL101 in Patients With Adenoid Cystic Carcinoma (ACC) Bearing Activating Notch Mutations

Clinical Trial Summary

This is a Phase 2, non comparative, open label, multicenter study of AL101 in patients with recurrent or metastatic ACC who harbor NOTCH 1,2,3,4 activating mutations.

Clinical Trial Description

This is a Phase 2, non-comparative, open-label, multicenter study of AL101 in patients with recurrent or metastatic ACC who harbor NOTCH 1,2,3,4 activating mutations. The study includes 2 cohorts, ran in a sequential fashion: Cohort 1 - AL101 4 mg once weekly (QW) intravenously (IV) Cohort 2 - AL101 6 mg QW IV ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03691207
Study type Interventional
Source Ayala Pharmaceuticals, Inc,
Contact
Status Completed
Phase Phase 2
Start date December 14, 2018
Completion date December 2, 2022
View Details
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