Acute Respiratory Infection Clinical Trial
Official title:
Maltese Antibiotic Stewardship Programme in the Community (MASPIC): a Prospective Quasi-experimental Social Marketing Intervention
Antibiotic resistance has become a major threat to global public health. It is driven by a
multitude of factors, however one of the leading factors is antibiotic prescribing.
Inappropriate antibiotic use and overuse of broad-spectrum antibiotics can lead to the
development of resistant strains. Since in Malta the vast majority of antibiotics are
acquired through prescription, targeting providers' prescribing behavior is an important
strategy needed to try to curb antibiotic overuse and resistance.
The aim of this study is to evaluate the effect of a multifaceted social marketing
intervention in changing general practitioners' (GPs) antibiotic prescribing behavior for
patients with acute respiratory tract complaints in Malta. This quasi-experimental
intervention study using an interrupted time series design includes three phases; a formative
pre-intervention phase, an intervention phase and post-intervention evaluation phase, and
will last a total of four years.
During the pre-intervention phase, various stakeholders, including GPs, pharmacists and
parents will be interviewed in order to get a better contextual understanding of antibiotic
use in Malta. A 1-year baseline surveillance system will also be set up to collect actual
diagnosis-specific antibiotic prescribing by GP. This data will, at a later stage, be used to
measure the change in antibiotic prescribing behavior post-intervention stage. GPs stage of
behavior change and intention to prescribe antibiotics will also be measure pre-intervention
using questionnaires based on the theory of planned behavior and the transtheoretical model.
The intervention stage will last 6 months and will include multiple components, including,
delayed prescription pads, educational sessions, educational materials for patients and
distribution of antibiotic guidelines. The intervention will be monitored closely through
numerous process indicators.
Following the intervention, GPs' stage of change and intention to prescribe antibiotics will
be re-measured using the same questionnaire used pre-intervention. Surveillance data
collection will be also be resumed and will provide data to measure the primary outcome as
well as additional secondary outcomes.
The primary outcome of interest is the change in the rate of antibiotic prescribing for
patients presenting with an acute respiratory tract complaint.
n/a
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