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Neural Pressure Support, Synchrony and Respiratory Muscle Unloading — NPS  

Acute Respiratory Failure Clinical Trial

Official title:
Neural Pressure Support, a Randomized Crossover Trial

Clinical Trial Summary

In this study patients who are intubated and on ventilator for more than 24h will be ventilated at three different level of support in Pressure Support and Neural Pressure Support to study patient-ventilator synchrony and muscle unloading.

Clinical Trial Description

This study is an interventional randomized crossover study in intubated and mechanically ventilated patients for more than 24h. Eligible patients from whom informed consent is obtained and Pes and Edi catheter are successfully positioned are enrolled in the study. Patients will be ventilated in Pressure Support and Neural Pressure Support at three different level of assist (baseline, 50% and 150% of baseline respectively) in randomized order. Ventilator curves will be recorded and bloodgas obtained at the end of each study step, each lasting 20min. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05670093
Study type Interventional
Source Karolinska Institutet
Contact Campoccia Jalde
Phone +46703947741
Email francesca.campoccia-jalde@regionstockholm.se
Status Recruiting
Phase N/A
Start date May 17, 2022
Completion date December 30, 2024
View Details
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