METEOR Think NIV Pilot

Status Completed

Clinical Trial Summary

This study will pilot test three strategies designed to speed implementation of preventive post-extubation noninvasive ventilation (NIV): one control strategy (traditional online continuing medical education) and two novel strategies (interprofessional education and just-in-time education).

Clinical Trial Description

During a one-month intervention period, the investigators will pilot test the educational strategies in three participating UPMC ICUs. Prior to receiving education, participants will be invited to complete a short online survey. Participants in the control group will be invited to complete a 30-minute online continuing education module, which will conclude with a survey. Participants in the interprofessional education group will be invited to attend a 90-minute, in-person, interprofessional education session that will occur in or near the participating ICU. A trained advance practice provider will provide participants in the just-in-time education group with 5-10 minutes of education in the ICU when the ICU team is rounding on a patient who is identified to be high risk for extubation failure. The just-in-time education may occur more than once per day, depending on the number of high-risk patients identified. All educational strategies will include content on the benefits of preventive post-extubation NIV, the indications and contraindications for preventive post-extubation NIV, and the value of working together as an interprofessional ICU team when implementing preventive post-extubation NIV. Each educational intervention will include a survey designed to determine the feasibility, acceptability, and preliminary impact of the educational strategies. The investigators will also directly observe instances of interprofessional and just-in-time education and conduct in-person interviews to assess these factors in a qualitative manner. Lastly, during the intervention period and the 6 months before and after the intervention period, the investigators will collect data from the electronic health record and analyze changes in percent of high-risk patients who receive preventive post-extubation NIV, reintubation rate, duration of mechanical ventilation, ventilator-associated pneumonia, and in-hospital mortality. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04052542
Study type	Interventional
Source	University of Pittsburgh
Contact
Status	Completed
Phase	N/A
Start date	August 28, 2019
Completion date	November 20, 2019

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05144633` - Blue Protocol and Eko Artificial Intelligence Are Best (BEA-BEST)
Completed	`NCT04534569` - Expert Panel Statement for the Respiratory Management of COVID-19 Related Acute Respiratory Failure (C-ARF)
Recruiting	`NCT03021902` - Nutrition and Exercise in Critical Illness	Phase 2
Completed	`NCT02902146` - Bougie Use in Emergency Airway Management	N/A
Completed	`NCT02901158` - Esophageal Manometry in Mechanically Ventilated Patients
Completed	`NCT02236559` - High Flow Therapy for the Treatment of Respiratory Failure in the ED	N/A
Recruiting	`NCT02056093` - Comparison of Proportional Assist Ventilation And Neurally Adjusted Ventilator Assist	N/A
Terminated	`NCT01083277` - Variable Ventilation During Acute Respiratory Failure	N/A
Not yet recruiting	`NCT01668368` - Goal Directed Mechanical Ventilation Aimed at Optimal Lung Compliance	N/A
Completed	`NCT01462279` - Effect of Thiamine on Oxygen Utilization (VO2) in Critical Illness	N/A
Completed	`NCT01114022` - Prevention Inhalation of Bacterial by Using Endotracheal Tube Balloon Polyvinyl Chloride or Polyurethane	N/A
Active, not recruiting	`NCT01058421` - Treatment of Critical Illness Polyneuromyopathy	Phase 2
Completed	`NCT00252616` - Timing of Target Enteral Feeding in the Mechanically Ventilated Patient	Phase 2/Phase 3
Recruiting	`NCT04098094` - Outcomes of RV Dysfunction in Acute Exacerbation of Chronic Respiratory Diseases
Recruiting	`NCT06051292` - Decremental Esophageal Catheter Filling Volume Titration For Transpulmonary Pressure Measurement	N/A
Completed	`NCT04601090` - Survival Rates and Longterm Outcomes After COVID-19
Recruiting	`NCT05423301` - Global Physiotherapy in ICU Patients With High Risk Extubation Failure	N/A
Completed	`NCT02447692` - Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation: The PROMIZING Study	N/A
Completed	`NCT04016480` - HFNC During Bronchoscopy for Bronchoalveolar Lavage	N/A
Completed	`NCT04507425` - High Flow Nasal Cannula With Noninvasive Ventilation	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.