Acute Respiratory Failure Clinical Trial
Official title:
Clinical Evaluation of an Automated Knowledge-based Computer Driven System (SmartCare/PS-NIV) Designed to Automatically Adapt Pressure Support Level and Expiratory Cycling During Non Invasive Ventilation, a Feasability Study.
Knowledge-based systems were initially developped to automatically adapt pressure support
settings during invasive ventilation, and proved to be at least as efficient as experienced
clinicians.
Non-invasive ventilation has become the standard of care for patients suffering from acute
hypercapnic respiratory failure (ARF)and has reduced the need for endotracheal intubation in
these patients, thus reducing their hospital mortality.
NIV success or failure is closely related to the tolerance of NIV treatment, which is
tightly correlated to patient-ventilator synchrony. As severe asynchronies frequently occurs
during NIV (namely in more than 40% of patients) and as the occurence of asynchronies is
related to the use of high pressure support levels, to the presence of leaks and/or to non
optimal expiratory trigger settings, very frequent ventilator settings adaptations should
allow reducing patient-ventilator asynchronies but require the presence of an experienced
clinician at the bedside during NIV treatment.
A computer-driven ventilator settings adaptation has the adavantage of permitting very
frequent ventilator settings adaptation whithout requiring the presence of an experienced
clinician at the bedside and could possibly improve patient-ventilator interaction.
The aim of the present study is to test the faisability of using the Smartcare NIV
computer-driven system to automatically adapt ventilator settings during non invasive
ventilation delivered because of acute respiratory failure.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05144633 -
Blue Protocol and Eko Artificial Intelligence Are Best (BEA-BEST)
|
||
| Completed |
NCT04534569 -
Expert Panel Statement for the Respiratory Management of COVID-19 Related Acute Respiratory Failure (C-ARF)
|
||
| Recruiting |
NCT03021902 -
Nutrition and Exercise in Critical Illness
|
Phase 2 | |
| Completed |
NCT02902146 -
Bougie Use in Emergency Airway Management
|
N/A | |
| Completed |
NCT02901158 -
Esophageal Manometry in Mechanically Ventilated Patients
|
||
| Completed |
NCT02236559 -
High Flow Therapy for the Treatment of Respiratory Failure in the ED
|
N/A | |
| Recruiting |
NCT02056093 -
Comparison of Proportional Assist Ventilation And Neurally Adjusted Ventilator Assist
|
N/A | |
| Terminated |
NCT01083277 -
Variable Ventilation During Acute Respiratory Failure
|
N/A | |
| Not yet recruiting |
NCT01668368 -
Goal Directed Mechanical Ventilation Aimed at Optimal Lung Compliance
|
N/A | |
| Completed |
NCT01462279 -
Effect of Thiamine on Oxygen Utilization (VO2) in Critical Illness
|
N/A | |
| Completed |
NCT01114022 -
Prevention Inhalation of Bacterial by Using Endotracheal Tube Balloon Polyvinyl Chloride or Polyurethane
|
N/A | |
| Active, not recruiting |
NCT01058421 -
Treatment of Critical Illness Polyneuromyopathy
|
Phase 2 | |
| Completed |
NCT00252616 -
Timing of Target Enteral Feeding in the Mechanically Ventilated Patient
|
Phase 2/Phase 3 | |
| Recruiting |
NCT04098094 -
Outcomes of RV Dysfunction in Acute Exacerbation of Chronic Respiratory Diseases
|
||
| Recruiting |
NCT06051292 -
Decremental Esophageal Catheter Filling Volume Titration For Transpulmonary Pressure Measurement
|
N/A | |
| Completed |
NCT04601090 -
Survival Rates and Longterm Outcomes After COVID-19
|
||
| Recruiting |
NCT05423301 -
Global Physiotherapy in ICU Patients With High Risk Extubation Failure
|
N/A | |
| Completed |
NCT02447692 -
Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation: The PROMIZING Study
|
N/A | |
| Completed |
NCT04016480 -
HFNC During Bronchoscopy for Bronchoalveolar Lavage
|
N/A | |
| Completed |
NCT04507425 -
High Flow Nasal Cannula With Noninvasive Ventilation
|
N/A |